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The principal cytochrome P450 isoenzyme included seems to generally be CYP2E1, with CYP1A2 and CYP3A4 as more pathways. Roughly 85% of an oral dose appears during the urine within just 24 hours of administration, most given that the glucuronide conjugate, with smaller quantities of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity i